\n\tThere are two relatively standard approaches for dealing with missing data in statistics, one based on “selection models” and one based on “pattern-mixture" models. The former is focused on formulating a model for complete data and then effectively imputing missing data so that the combined observed and missing data fit the assumed model for the complete data. In contrast, the latter effectively fits a different model for each pattern of observed and missing data, thereby directly revealing sensitivity of conclusions to assumptions about distributions for which there are no actual observed data available for estimation. A third class of models, which have remained mostly recondite, is based on “Gibbs” factorizations; although these may not imply a valid joint distribution, they have enjoyed success in applications because of their ease of use when implemented by MCMC computer software for multiple imputation, such as in SAS, STATA, and MICE. The consideration of sensitivity of conclusions to assumptions unassailable by observed data, whether implicit, as with selection models, or explicit, as with pattern-mixture models, is a critical ingredient of satisfactory analyses of data sets with missing values. Graphical displays, such as “enhanced tipping point analyses” implemented using modern computing, are critical ingredients for this enterprise.\n<\/div>\n
\n嘉宾介绍： Don B. Rubin is John L. Loeb Professor at Harvard University,
\n美国国家科学院院士, 美国艺术及科学院院士, 美国美国科学促进会会士.
\nProfessor Rubin is one of the most influential living statisticians in the world. He has made the many fundamental contributions to the modern world of statistics, particularly in the areas of missing data and causal inference. He has published over 400 papers and is most highly cited author in the world with currently over 20,000 citations in 2016 alone.